Pharmaceuticals

Pharmaceuticals

Amber colored glass pharmaceutical bottles in a lab

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Pharmaceuticals are substances used in the diagnosis, treatment and/or prevention of diseases in humans and animals. Can also be referred to as drugs and medications.

Pumps are used to manufacture both chemically-synthesized drugs and biological-based drugs or biopharmaceuticals. Liquid characteristics vary greatly but are often viscous, shear-sensitive and extremely sensitive to bacterial contamination. Many chemically-synthesized drugs are made purely from dry powder-based materials but may use pumps to deliver coatings or they may be blended into liquid materials and pumped for oral, topical, ophthalmic, nasal, injection or other delivery methods.

Biopharmaceuticals are viscous suspensions of biological materials that are grown in bioreactors and product is extracted through a variety of clarification and purification stages.

Hygienic positive displacement pumps are well suited to handle all of these liquids and compounds due to their ability to handle a broad range of viscosities with extremely low shear so they don’t damage sensitive cell cultures. Some configurations are self-draining to eliminate holdup volume of costly materials. Their flow rates may be easily controlled using variable speed drives for metering applications.

To protect against contamination, Viking hygienic pumps meet critical hygiene requirements, including Regulatory Compliance (3-A Sanitary Standards, USP Class VI materials, ATEX and CE certifications); Sanitary Design (surface finish requirements for cleanability, CIP/SIP system integration, material compatibility); and Documentation Support (material certifications and traceability, performance validation data, installation and maintenance documentation).

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    Viking in the Process

    Viking pumps are used in chemically-derived pharmaceuticals primarily for blending active ingredients into liquid delivery methods by transferring those liquids to blending vessels and then pumping to packaging machines. Viking pumps are used in biopharma for transferring cell culture materials to bioreactors and transferring resulting cell cultures through various further processing steps like cell harvesting, lysis, recovery, clarification, and purification.

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      Applications

      • Polymeric pill coatings
      • Oral suspensions
      • Topical lotions, creams and ointments
      • Opthalmic, nasal and otic solutions
      • Water for Injection (WFI)
      • Cell culture media
      • Parenteral medications
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